Two factors each have a significant impact on the pCO2. The first is how rapidly and deeply the individual is breathing:. PO2 partial pressure of oxygen reflects the amount of oxygen gas dissolved in the blood. It primarily measures the effectiveness of the lungs in pulling oxygen into the blood stream from the atmosphere. CO2 content is a measurement of all the CO2 in the blood. Most of this is in the form of bicarbonate HCO3 , controlled by the kidney.
For this reason, changes in CO2 content generally reflect such metabolic issues as renal function and unusual losses diarrhea. Respiratory disease can ultimately effect CO2 content, but only slightly and only if prolonged. Whenever there is an accumulation of metabolically produced acids, the body attempts to neutralize those acids to maintain a constant acid—base balance. This neutralizing is achieved by using up various "buffering" compounds in the blood stream, to bind the acids, disallowing them from contributing to more acidity.
This machine also measures electrolytes, including ionized calcium, using ion-selective electrodes on undiluted samples direct potentiometry.
This is because ionized calcium values are altered by pH increase in states of acidosis. Furthermore, an anion gap is calculated from the results. We have reference intervals for dogs, cats, horses and cattle for venous blood only. In general, arterial blood gases are preferred for blood gas measurement, especially if you are concerned about the oxygen status of the animal. Venous blood gas results differ from arterial blood gas results, because the sample is affected by tissue metabolism.
Therefore, the blood is more acidic and the oxygen content lower in the venous circulation. Click on the highlighted panel below to obtain more information about the test components. For more information about blood gases and interpretation of acid base abnormalities, refer to Bicarbonate under our Chemistry section of eClinPath. Phone: Fax: Email: diagcenter cornell. Values of partial pressure of oxygen PO2 and of carbon dioxide PCO2 were measured by means of blood gas electrodes.
The correlation coefficients between the two samples were 0. In spite of a highly significant correlation, the limits of agreement between the two methods were wide for PO2.
Clin Chem ; Disclaimer May contain information that is not supported by performance and intended use claims of Radiometer's products. Chris Higgins has a master's degree in medical biochemistry and he has twenty years experience of work in clinical laboratories. Sign up for the Acute Care Testing newsletter Sign up.
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