Already a member or subscriber? Log in. Interested in AAFP membership? Learn more. POEMs patient-oriented evidence that matters are provided by EssentialEvidence Plus, a point-of-care clinical decision support system published by Wiley-Blackwell. Copyright Wiley-Blackwell. Used with permission. Severe but less common side effects can occur with Vicodin and Percocet medications. If you have any of these side effects, call or go to the nearest emergency room right away. These side effects may include:.
Both Vicodin and Percocet affect your mental and physical abilities, such as judgment and reflexes. Vicodin and Percocet are powerful drugs, so you should be aware of the risks involved with taking them. Even if you take them exactly as prescribed, Vicodin or Percocet may become habit-forming.
In other words, these drugs can cause physical or mental dependence. For this reason, doctors are cautious when prescribing them. There is also the risk of a withdrawal response when stopping these drugs.
If you take either drug for more than a few days, talk to your doctor before you stop. Your doctor can help you taper off the medication slowly. This reduces your risk of withdrawal. Be sure to take these drugs exactly as your doctor prescribes to reduce your risk of both dependence and withdrawal problems.
Like most drugs, Vicodin and Percocet can interact with other medications. This means that when used with certain other drugs, these medications can cause effects that can be dangerous. Before you take Vicodin or Percocet, tell your doctor about all other medications you take, including vitamins and supplements. Vicodin and Percocet interact with many of the same drugs. For more information, visit the interaction sections for Vicodin and Percocet. If you have certain health conditions, taking Vicodin or Percocet could increase certain risks.
Before taking Vicodin or Percocet, be sure to tell your doctor if you have constipation or intestinal blockage. Opioid analgesics can cause increased constipation, so ask your doctor if you should avoid taking them.
You should not drink alcohol while taking either Vicodin or Percocet. Combining alcohol and these painkillers can cause extreme dizziness or drowsiness, and can even be deadly. In some cases, taking one of these drugs with alcohol can cause liver damage.
There was no difference between the two groups in age, weight, gender, ethnicity, diagnoses, baseline pain scores, or vital signs.
Patients in both groups had pain relief from baseline to 30 minutes oxycodone mean change 3. There was no difference in pain between the patients treated with oxycodone and hydrocodone at 30 minutes mean difference between groups Conclusions: Treatment with acetaminophen and either oxycodone, 5 mg po, or hydrocodone, 5 mg po, resulted in pain relief among ED patients with acute fractures, and there was no difference between the two agents at 30 and 60 minutes.
The key difference between the two drugs is that Percocet contains the opioid oxycodone, while Vicodin contains the opioid hydrocodone. Both also contain acetaminophen. The amount of acetaminophen in Percocet or Vicodin varies, depending on the formula. Percocet is available in formulas containing milligrams mg of acetaminophen, while Vicodin may contain or mg of acetaminophen. These doses of acetaminophen are similar to that of extra-strength Tylenol , which comes in mg caplets.
An adult may safely take a maximum of two of these caplets every 6 hours. People should be sure to read the instructions that come with the product, as different products have different instructions. It is also crucial to:. The right dosage of Vicodin or Percocet depends on the formula the doctor selects.
Generally, doctors recommend taking opioids only as needed, rather than continually. People typically take Percocet and Vicodin every 4—6 hours , or less frequently if there is less need. While taking either drug, avoid any other products that contain acetaminophen. According to the FDA, the current maximum adult dosage of acetaminophen is 4, mg per day. To help avoid taking too much acetaminophen, the makers of extra-strength Tylenol have lowered their maximum daily dose to six pills, which works out as 3, mg per day.
The United States is experiencing an epidemic of fatal opioid overdoses. In , 67, people died of drug overdoses, and around 9. Both Vicodin and Percocet can be highly addictive and very dangerous at high doses.
The acetaminophen in these drugs makes them even more dangerous — taking more than the maximum daily dosage of 3,—4, mg of acetaminophen can cause fatal liver damage. Both Percocet and Vicodin may interact with any drug that slows down activity in the central nervous system, including:.
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